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Diabetes insipidus is rare in cats and is characterized by excessive drinking and the production of enormous volumes of extremely dilute urine. Despite drinking large volumes of water, the cat can become dehydrated from urinating so much. Increased drinking and urination are common signs of several other health conditions, so it is essential that several diagnostic tests be performed to diagnose diabetes insipidus. While the condition is rarely curable, it is usually successfully controlled.
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Diabetes mellitus results from an inadequate production of insulin from the pancreas. The primary treatment is replacement by insulin injections. The body's response to the injections needs to be regularly monitored using an at-home glucometer or continuous glucose monitoring system. Insulin must be stored and reconstituted carefully to ensure dosing is accurate. Giving subcutaneous injections of insulin can seem daunting at first, but by following the directions in this handout, it will quickly become second nature to both you and your pet.
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New medications can help regulate blood glucose levels in cats, including once-daily oral medications bexagliflozin (Bexacat) and velagliflozin (Senvelgo). Cats in the initial stages of DM may benefit most from oral diabetes treatments. This article discusses how these medications work, potential risks, and monitoring required.
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Diabetes mellitus is an inability to regulate blood glucose caused by a loss of insulin production (Type I) or inadequate insulin supply or resistance (Type II). In cats, diabetes mellitus is most often type II. This type of diabetes usually results from obesity, creating insulin resistance. Cats with type II may be treated with oral medication, but some cats may ultimately require insulin injections. Diet is also important. This article discusses various treatments and monitoring regimens.
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Diabetic ketoacidosis is a medical emergency that occurs when there is not enough insulin, or the available insulin isn’t effective enough to control blood sugar (glucose) levels. Your veterinarian needs to perform appropriate tests to diagnose this disease, as similar signs can occur with other medical conditions. Treatment involves hospitalization with IV fluids, short-acting insulin and electrolyte replacement. The most important step in prevention is ensuring careful insulin dosing and disease monitoring.
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Diazepam is given by mouth, injection, or into the rectum and is used off label to treat anxiety, seizures, tense muscles, or decreased appetite. Give as directed by your veterinarian. Side effects include sleepiness, increased appetite, incoordination, weakness, agitation, drooling, and aggression. Do not give to cats by mouth, and do not use in pets that are allergic to it or other benzodiazepines, or in pets with severe liver disease. If a negative reaction occurs, please call your veterinary office.
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Diazoxide is given by mouth and is used off label to treat low blood sugar associated with insulin-producing tumors of the pancreas. Give as directed by your veterinarian. Common side effects include drooling, lack of appetite, vomiting, and diarrhea. Do not use in pets that are allergic to it or thiazide diuretics, or in pets with low blood sugar due to anything other than a tumor. If a negative reaction occurs, please call your veterinary office.
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Diclofenac ophthalmic is a topical nonsteroidal anti-inflammatory medication used to treat inflammatory eye conditions in cats, dogs, rabbits, avian species, and other animals. Diclofenac ophthalmic comes in liquid drop form.
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Digoxin is used off label and is given by mouth or injection to treat certain abnormal heart rhythms and certain types of congestive heart failure. Common side effects include vomiting, diarrhea, lack of appetite, weight loss, tiredness, or behavior changes.
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Diltiazem is given by mouth as a tablet, capsule, or compounded liquid, and is used off label to treat abnormal heart rhythms, high blood pressure, and other heart conditions. Common side effects include a slow heart rate in dogs and vomiting in cats. This medication should not be used in pets with hypersensitivity, severely low blood pressure, lung congestion, or certain abnormal heart rhythms.