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  • Rifampin is commonly used off label to treat infections in horses, and occasionally in dogs and cats. It is usually given by mouth in the form of a capsule or compounded liquid. The most common side effects are vomiting, diarrhea, or reduced appetite. Liver dysfunction is possible. A change in the color of urine, tears, and saliva to a red/orange color is expected but may stain fabrics. Use with caution in pets that have pre-existing liver disease, are pregnant, are elderly, or are lactating. If a negative reaction occurs, call your veterinary office.

  • Anesthesia-free dentistry is commonly offered at pet stores and grooming facilities. It is more limited than veterinary dentistry, and often a higher-stress option with more potential for injury from sharp instruments. Dental cleanings should only be performed while your pet is under anesthesia. Your veterinarian will customize your pet's anesthetic plan for your pet's overall health.

  • Robenacoxib (brand name: Onsior) is given by mouth in the form of a tablet to treat pain and inflammation associated with surgery or other musculoskeletal conditions in dogs and cats. Do not use this medication in pets that are allergic to it, or in pets concurrently using corticosteroids or other NSAIDs. If a negative reaction occurs, call your veterinary office.

  • Ronidazole is given by mouth and is used off label to treat Tritrichomonas foetus, trichomonas, and giardia in dogs, cats, and birds. It should not be used in farmed animals. Common side effects include vomiting and decreased appetite. Do not use in pets that are allergic to it or other nitroimidazoles such as metronidazole. If a negative reaction occurs, please call your veterinary office.

  • SAMe is given by mouth and is used on label and over the counter to treat liver disease and other conditions. Give as directed by your veterinarian. Side effects are uncommon but may include mild stomach upset. Antidepressants, dextromethorphan, meperidine, pentazocine, and tramadol should be used with caution when given with SAMe. Inform your veterinarian of all medications, vitamins, and supplements that your pet is taking. If a negative reaction occurs, please call your veterinary office.

  • SAMe or S-adenosyl-methionine + Silybin (brand name: Denamarin®) is a combination supplement commonly used to support liver health in cats and dogs. The body uses SAMe for many important functions, such as brain, heart, hormone, antioxidant, detoxifying, and other metabolic functions. The combination of SAMe and Silybin is used to support liver and brain health. This article discusses side effects, interactions, monitoring, and storage.

  • Do you have medications stored in the bathroom cabinet, kitchen drawer, and pantry shelf? Are random bottles haphazardly tossed into the “pharmacy”? Medications are meant to help us and our pets, but they can do more harm than good if stored or administered incorrectly. You can protect your family and pets by safely handling and disposing of medications.

  • Sago Palms are pretty plants but beware—they pack a deadly punch for pets. The popular Sago Palm enhances outdoor landscapes in warmer areas of the U.S. and serves as indoor decor in many colder climates. All parts of the Sago Palm are poisonous, but the seeds (nuts) are the most toxic to pets. As with all poisoning cases, early detection and treatment increases the rate of success.

  • Salicylic acid topical (brand name Solva-Ker®, BioSeb®, Cerasoothe® SA, others) is an antimicrobial and antipruritic (anti-itching) agent used in the treatment of seborrheic (dry or greasy dandruff) disorders in cats, dogs, and other animals. It may be specially compounded and/or combined into a formulation with other medications. It comes in cream, gel, ointment, and shampoo forms.

  • Salivary gland tumors are rare in dogs and cats. The mandibular and parotid glands are most commonly affected. Signs include swelling of the upper neck or ear base, halitosis, anorexia, weight loss, difficulty eating, pain, and lethargy. The treatment of choice is usually surgical excision. If complete excision is not possible, adjunct radiation therapy may be pursued.