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  • Salicylic acid topical (brand name Solva-Ker®, BioSeb®, Cerasoothe® SA, others) is an antimicrobial and antipruritic (anti-itching) agent used in the treatment of seborrheic (dry or greasy dandruff) disorders in cats, dogs, and other animals. It may be specially compounded and/or combined into a formulation with other medications. It comes in cream, gel, ointment, and shampoo forms.

  • Salivary gland tumors are rare in dogs and cats. The mandibular and parotid glands are most commonly affected. Signs include swelling of the upper neck or ear base, halitosis, anorexia, weight loss, difficulty eating, pain, and lethargy. The treatment of choice is usually surgical excision. If complete excision is not possible, adjunct radiation therapy may be pursued.

  • A salivary mucocele is an accumulation of saliva that has leaked from an injured salivary gland or duct. Some mucoceles cause swelling of the face and neck, while others interfere with a dog's ability to swallow or breathe normally. Treatment typically requires surgical removal of the affected salivary gland(s).

  • SAMeLQ® is a supplement for dogs and cats that supports normal liver function. It contains ingredients like S-Adenosyl Methionine (SAMe), licorice root extract, quercetin, L-taurine, B-vitamins, and other antioxidants.

  • Seboliance (brand name Douxo®S3 SEB) is a natural extract from the pomegranate plant (Punica granatum) used to help control dandruff, reduce odor, and help hydrate dry skin in cats and dogs. Seboliance may be part of a combination product containing ophytrium. Seboliance comes in mousse and shampoo forms.

  • Selamectin (brand names: Revolution®, Paradyne®, Stronghold®, Chanhold®) is an avermectin antiparasitic used topically to treat parasites in dogs and cats, both on and off label. Use with caution in sick or underweight pets, or dogs with the MDR1 mutation.

  • Selamectin + sarolaner is used topically on the skin to treat various parasites, both on and off-label, and prevent heartworm in cats. Side effects are rare but may include hair loss at the application site, gastrointestinal upset, skin reactions, or neurologic signs. It should be used with caution in sick or underweight cats. If a negative reaction occurs, please call your veterinary office.

  • Selegiline is typically given by mouth and is used off and on label in dogs and cats to treat signs due to cognitive dysfunction syndrome, pituitary-dependent Cushing’s disease, anxiety, and certain phobias.

  • Serotonin is a neurotransmitter produced by the body that regulates mood, sleep, body temperature, pain perception, blood vessel constriction, gastrointestinal function, and even blood clotting. An animal with serotonin syndrome experiences excessive effects of serotonin. This handout reviews the causes, diagnosis and treatment.

  • Sertraline is given by mouth and is an antidepressant used off label in dogs and cats to treat a variety of behavior disorders, including anxiety, obsessive compulsive disorder, and aggression.